Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 14/20 | 0.70 |
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL317530 | 0.82 | OPRL1 (1.00) | OPRL1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL4056482 | 0.81 | OPRL1 (0.96) | OPRL1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL27606554 | 0.81 | OPRL1 (0.96) | OPRL1OPRM1OPRK1 | |
| Cyanide SCHEMBL28243987 | 0.78 | OPRL1 (0.90) | OPRL1OPRM1OPRK1 | |
| SCHEMBL14337143 | 0.74 | OPRL1 (0.67) | OPRL1KDM1AMAOBMAOA | |
| SCHEMBL423267 | 0.70 | OPRL1 (0.60) | OPRL1KDM1AMAOBOPRM1MAOA | |
| SCHEMBL5054294 | 0.70 | OPRL1 (0.59) | OPRL1KDM1AMAOBOPRM1OPRK1 | |
| SCHEMBL5052795 | 0.70 | OPRL1 (0.59) | OPRL1KDM1AMAOBOPRM1OPRK1 | |
| SCHEMBL23699058 | 0.69 | OPRL1 (0.65) | OPRL1OPRM1OPRK1 | |
| SCHEMBL4352329 | 0.69 | OPRL1 (0.65) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7476763-B2 | Oxo-substituted cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2009-01-13 | — | — | US | disclosed |
| US-20070088034-A1 | Oxo-substituted cyclohexyl-1,4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088034-A1 | Oxo-substituted cyclohexyl-1,4-diamine compounds | AOC1, ODC1, OTC | OPRL1 782/4885KDM1A 1638/4885MAOB 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.