Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 12/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9140846 | 0.77 | MCL1 (0.36) | GAA | |
| SCHEMBL30943031 | 0.76 | MEN1 (0.37) | EPHX1EPHX2 | |
| SCHEMBL5076250 | 0.76 | MCL1 (0.42) | GAAEPHX1 | |
| SCHEMBL14424448 | 0.72 | EPHX1 (0.51) | EPHX1EPHX2 | |
| SCHEMBL5078153 | 0.70 | EPHX1 (0.43) | EPHX1EPHX2 | |
| SCHEMBL28863518 | 0.70 | KMT2A (0.47) | POLBGAATDP1 | |
| SCHEMBL28004819 | 0.70 | EPHX1 (0.49) | EPHX1EPHX2 | |
| SCHEMBL3483037 | 0.70 | EPHX1 (0.45) | EPHX1EPHX2 | |
| SCHEMBL14424480 | 0.68 | EPHX1 (0.54) | EPHX1EPHX2 | |
| SCHEMBL4046183 | 0.68 | NAAA (0.38) | EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713815-A4 | PTH AGONISTS | SMITHKLINE BEECHAM CORP (US) | 2009-03-11 | — | — | EP | disclosed |
| US-20070099940-A1 | Pth agonists | SPEARING PAUL K | 2007-05-03 | — | — | US | disclosed |
| EP-1713815-A1 | PTH AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005077959-A1 | PTH AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099940-A1 | Pth agonists | PTH1R, CALCR, SSTR3 | POLB 4593/4885GAA 4790/4885TDP1 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.