⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7576178 | 0.82 | CA2 (0.35) | — | |
| SCHEMBL16796732 | 0.81 | — | — | |
| SCHEMBL29086760 | 0.76 | — | — | |
| SCHEMBL11013961 | 0.76 | — | — | |
| SCHEMBL26947095 | 0.75 | — | — | |
| SCHEMBL6524981 | 0.74 | — | — | |
| SCHEMBL17354689 | 0.73 | — | — | |
| SCHEMBL8562135 | 0.73 | — | — | |
| SCHEMBL6309278 | 0.73 | — | — | |
| SCHEMBL9047080 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382967-B | Carbazole sulfonamide derivative or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 中国医学科学院医药生物技术研究所 | 2021-02-19 | — | — | CN | disclosed |
| EP-2010532-A1 | TRYCLIC NITROGEN CONTAINING COMPOUNDS AND THEIR USE AS ANTIBACTERIALS | Glaxo Group Limited (GB) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007122258-A1 | TRYCLIC NITROGEN CONTAINING COMPOUNDS AND THEIR USE AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2007-11-01 | — | — | WO | disclosed |
| WO-2003018521-A1 | SUBSTITUTED ALKENE DIOLS | ISIS INNOVATION LIMITED (GB) | 2003-03-06 | — | — | WO | disclosed |
| EP-1043990-A1 | PYRONIN ANTIBACTERIALS, PROCESS AND NOVEL INTERMEDIATES THERETO | Scriptgen Pharmaceuticals, Inc. (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999034793-A1 | PYRONIN ANTIBACTERIALS, PROCESS AND NOVEL INTERMEDIATES THERETO | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1999-07-15 | — | — | WO | disclosed |
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | disclosed |
| EP-0723545-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-07-31 | — | — | EP | disclosed |