Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 5/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 5/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690694 | 0.93 | CNR1 (0.39) | CNR1CNR2HTR3AHTR4F10 | |
| SCHEMBL13691310 | 0.91 | CNR1 (0.40) | CNR1CNR2HTR3AF10CFD | |
| SCHEMBL4058510 | 0.91 | CNR1 (0.48) | CNR1CNR2HTR3AMMP2MMP3 | |
| SCHEMBL13690652 | 0.89 | CNR1 (0.40) | CNR1CNR2HTR4 | |
| SCHEMBL4052327 | 0.89 | CNR1 (0.40) | CNR1CNR2HTR4 | |
| SCHEMBL4059133 | 0.89 | HTR4 (0.42) | CNR1CNR2HTR3AHTR4 | |
| SCHEMBL13690587 | 0.89 | HTR4 (0.42) | CNR1CNR2HTR3AHTR4 | |
| SCHEMBL4052559 | 0.89 | CNR1 (0.48) | CNR1CNR2 | |
| SCHEMBL4050200 | 0.89 | CNR1 (0.43) | CNR1CNR2CFD | |
| SCHEMBL4052469 | 0.89 | CNR1 (0.40) | CNR1CNR2HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |