Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.62 |
| ▸ | MAX | P61244 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.43 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4049619 | 1.00 | MYC (0.62) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL4049617 | 1.00 | MYC (0.62) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL4048429 | 1.00 | MYC (0.62) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL4057688 | 0.90 | MYC (0.61) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL4053142 | 0.88 | MYC (0.59) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL4050459 | 0.88 | MYC (0.59) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL4053139 | 0.88 | MYC (0.59) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL4051155 | 0.88 | MYC (0.59) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL6263164 | 0.84 | ALDH1A1 (0.77) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL6263166 | 0.84 | ALDH1A1 (0.77) | MYCMAXALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |