Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 16/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4049633 | 0.85 | ELANE (0.50) | ELANEF2PLAUCNR1CNR2 | |
| SCHEMBL13690858 | 0.83 | TSHR (0.47) | CNR1CNR2 | |
| SCHEMBL17321351 | 0.83 | ELANE (0.66) | ELANEF2PLAU | |
| SCHEMBL15882396 | 0.82 | ELANE (0.58) | ELANEF2PLAUCNR1CNR2 | |
| SCHEMBL6113989 | 0.82 | PARP1 (0.56) | ELANECNR1CNR2 | |
| SCHEMBL26258125 | 0.81 | ELANE (0.56) | ELANEF2PLAUCNR1CNR2 | |
| SCHEMBL15897943 | 0.81 | ELANE (0.57) | ELANEF2PLAUCNR1CNR2 | |
| SCHEMBL15882325 | 0.80 | ELANE (0.61) | ELANEF2PLAU | |
| SCHEMBL4052496 | 0.79 | TSHR (0.51) | CNR1CNR2 | |
| SCHEMBL8400360 | 0.78 | PARP1 (0.57) | ELANECNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |