Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.50 |
| ▸ | PLAU | P00749 | 3/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 7/20 | 0.47 |
| ▸ | CNR2 | P34972 | 5/20 | 0.47 |
| ▸ | HTR3A | P46098 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048620 | 0.85 | ELANE (0.55) | ELANEPLAUF2CNR1CNR2 | |
| SCHEMBL4052496 | 0.85 | TSHR (0.51) | CNR1CNR2HTR3AKDM4EPARP1 | |
| SCHEMBL18525606 | 0.84 | ELANE (0.52) | ELANEPLAUF2TSHR | |
| SCHEMBL3071892 | 0.84 | ELANE (0.53) | ELANEPLAUF2CNR1CNR2 | |
| SCHEMBL8400360 | 0.84 | PARP1 (0.57) | ELANECNR1CNR2HTR3AKDM4E | |
| SCHEMBL17287279 | 0.84 | CNR1 (0.60) | ELANEPLAUF2CNR1CNR2 | |
| SCHEMBL31429235 | 0.82 | ELANE (0.57) | ELANEPLAUF2CNR1CNR2 | |
| SCHEMBL13690858 | 0.81 | TSHR (0.47) | CNR1CNR2HTR3AKDM4EPARP1 | |
| SCHEMBL31429292 | 0.81 | ELANE (0.56) | ELANEPLAUF2CNR1CNR2 | |
| SCHEMBL3065175 | 0.81 | ELANE (0.50) | ELANEPLAUF2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |