SCHEMBL40492

SCHEMBL40492

[c]1ncccccccc1-c1ccccccccn1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.52
LMNA P02545 4/20 0.52
CCR1 P32246 3/20 0.52
CCR5 P51681 3/20 0.52
CCR8 P51685 3/20 0.52
METAP1 P53582 2/20 0.52
CYP1A2 P05177 1/20 0.52
POLB P06746 1/20 0.52
BLM P54132 1/20 0.52
HIF1A Q16665 1/20 0.52
DOHH Q9BU89 1/20 0.52
P4HTM Q9NXG6 1/20 0.52
TP53 P04637 6/20 0.50
TDP1 Q9NUW8 3/20 0.50
RAB9A P51151 7/20 0.45
NPC1 O15118 7/20 0.45
SMN1; SMN2 Q16637 6/20 0.45
ALOX15 P16050 4/20 0.45
L3MBTL1 Q9Y468 4/20 0.45
PKM P14618 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL155358 0.96 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL16026579 0.76 KDM4E (0.59) KDM4ELMNACCR1CCR5CCR8
SCHEMBL8599888 0.75 KDM4E (0.46) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL27971550 0.74 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL14841487 0.74 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
SCHEMBL186905 0.73 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8
SCHEMBL4909130 0.71
Dipyridyl SCHEMBL29907716 0.71 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL3711450 0.71 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29351528 0.71 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4319556-A1 USE OF ANTI-CLOTTING COMPOUNDS AS RODENTICIDES Gulba, Dietrich (DE) 2024-02-14 EP disclosed
US-10724903-B2 Polymer encapsulated particles as surface enhanced Raman scattering probes NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2020-07-28 US disclosed
US-10464811-B2 Method of forming a particulate porous metal oxide or metalloid oxide NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2019-11-05 US disclosed
EP-2909027-B1 ENCAPSULATION BARRIER STACK TERA BARRIER FILMS PTE LTD (SG) 2019-10-09 EP disclosed
EP-2771182-B1 ENCAPSULATION BARRIER STACK TERA BARRIER FILMS PTE LTD (SG) 2019-05-15 EP disclosed
US-20190027414-A1 ENCAPSULATION BARRIER STACK AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2019-01-24 US disclosed
EP-3154343-A1 USE AS RODENTICIDES OF COMPOUNDS THAT INHIBIT BLOOD COAGULATION Gulba, Dietrich (DE) 2017-04-19 EP disclosed
US-9334230-B2 Process of forming an amide NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2016-05-10 US disclosed
US-20160088756-A1 ENCAPSULATION BARRIER STACK COMPRISING DENDRIMER ENCAPSULATED NANOP ARTICLES TERA-BARRIER FILMS PTE LTD (SG) 2016-03-24 US disclosed
EP-2991824-A1 ENCAPSULATION BARRIER STACK COMPRISING DENDRIMER ENCAPSULATED NANOP ARTICLES Tera-Barrier Films Pte Ltd (SG) 2016-03-09 EP disclosed
US-20100298504-A1 AMPHIPHILIC POLYMER AND PROCESSES OF FORMING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-11-25 US disclosed
US-20100254890-A1 METHOD OF FORMING A PARTICULATE POROUS METAL OXIDE OR METALLOID OXIDE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2010-10-07 US disclosed
US-20100228058-A1 CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2010-09-09 US disclosed
WO-2010027326-A1 PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2010-03-11 WO disclosed
WO-2009142604-A1 POLYMER ENCAPSULATED PARTICLES AS SURFACE ENHANCED RAMAN SCATTERING PROBES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2009-11-26 WO disclosed
EP-2084105-A1 METHOD OF FUNCTIONALIZING A CARBON MATERIAL Agency for Science, Technology And Research (SG) 2009-08-05 EP disclosed
WO-2009078813-A1 METHOD OF FORMING OSELTAMIVIR AND DERIVATIVES THEREOF NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2009-06-25 WO disclosed
WO-2009038544-A1 AMPHIPHILIC POLYMER AND PROCESSES OF FORMING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2009-03-26 WO disclosed
WO-2008048192-A1 METHOD OF FUNCTIONALIZING A CARBON MATERIAL AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-04-24 WO disclosed
WO-2007097719-A1 CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2007-08-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100228058-A1 CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND DHPS, GGPS1, COASY KDM4E 2747/4885LMNA 2075/4885CCR1 2581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.