Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.57 |
| ▸ | CNR2 | P34972 | 6/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.47 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690572 | 1.00 | CNR1 (0.57) | CNR1CNR2PLA2G2AHTR3AMTNR1B | |
| SCHEMBL4056551 | 0.91 | CNR1 (0.55) | CNR1CNR2PLA2G2APOLBALDH1A1 | |
| SCHEMBL4049858 | 0.90 | CNR1 (0.51) | CNR1CNR2PLA2G2AHTR3AMTNR1B | |
| SCHEMBL13691245 | 0.90 | CNR1 (0.51) | CNR1CNR2PLA2G2AHTR3AMTNR1B | |
| SCHEMBL13690556 | 0.89 | CNR1 (0.49) | CNR1CNR2PLA2G2AHTR3AALDH1A1 | |
| SCHEMBL4059315 | 0.89 | CNR1 (0.49) | CNR1CNR2PLA2G2AHTR3AALDH1A1 | |
| SCHEMBL13691014 | 0.88 | CNR1 (0.60) | CNR1CNR2HTR3AHTR2CSLC6A4 | |
| SCHEMBL4053561 | 0.88 | CNR1 (0.60) | CNR1CNR2HTR3AHTR2CSLC6A4 | |
| SCHEMBL4050445 | 0.88 | CNR1 (0.59) | CNR1CNR2HTR2CSLC6A4 | |
| SCHEMBL13691249 | 0.88 | CNR1 (0.59) | CNR1CNR2HTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |