Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.45 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691245 | 1.00 | CNR1 (0.51) | CNR1PLA2G2AHTR3ACNR2ALDH1A1 | |
| SCHEMBL4052321 | 0.92 | CNR1 (0.49) | CNR1PLA2G2ACNR2ALDH1A1POLB | |
| SCHEMBL13690572 | 0.90 | CNR1 (0.57) | CNR1PLA2G2AHTR3ACNR2ALDH1A1 | |
| SCHEMBL4049548 | 0.90 | CNR1 (0.57) | CNR1PLA2G2AHTR3ACNR2ALDH1A1 | |
| SCHEMBL4050539 | 0.90 | CNR1 (0.47) | CNR1PLA2G2AHTR3ACNR2ALDH1A1 | |
| SCHEMBL4055448 | 0.89 | CNR1 (0.52) | CNR1CNR2ROCK1HTR2CSLC6A4 | |
| SCHEMBL13690575 | 0.88 | CNR1 (0.46) | CNR1PLA2G2AHTR3ACNR2ALDH1A1 | |
| SCHEMBL4059315 | 0.88 | CNR1 (0.49) | CNR1PLA2G2AHTR3ACNR2ALDH1A1 | |
| SCHEMBL13690556 | 0.88 | CNR1 (0.49) | CNR1PLA2G2AHTR3ACNR2ALDH1A1 | |
| SCHEMBL4051743 | 0.87 | CNR1 (0.67) | CNR1HTR3ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |