SCHEMBL404956

SCHEMBL404956

CC(C)C(C=CC(N)=O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 2/20 0.38
GABRD O14764 2/20 0.38
GABRA1 P14867 2/20 0.38
GABRB1 P18505 2/20 0.38
GABRG2 P18507 2/20 0.38
GABRB3 P28472 2/20 0.38
GABRA5 P31644 2/20 0.38
GABRA3 P34903 2/20 0.38
GABRA2 P47869 2/20 0.38
GABRB2 P47870 2/20 0.38
GABRA4 P48169 2/20 0.38
GABRE P78334 2/20 0.38
GABRA6 Q16445 2/20 0.38
GABRG1 Q8N1C3 2/20 0.38
GABRG3 Q99928 2/20 0.38
GABRQ Q9UN88 2/20 0.38
SLC7A5 Q01650 1/20 0.37
TP53 P04637 1/20 0.32
SLC1A3 P43003 1/20 0.30
SLC1A2 P43004 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6899896 0.85 TP53 (0.42) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL6899891 0.85 TP53 (0.42) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL18523397 0.76 TP53 (0.41) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL18523398 0.76 TP53 (0.41) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL16670214 0.76 SLC7A5 (0.36) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL16674847 0.76 SLC7A5 (0.36) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL16670213 0.76 SLC7A5 (0.36) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL19199018 0.73 GABRP (0.37) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL717707 0.72
SCHEMBL4114676 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2451887-B1 EMULSION STABILIZING AGENTS FOR DRILLING AND COMPLETION FLUIDS HALLIBURTON ENERGY SERV INC (US) 2014-04-30 EP claimed
US-20120264657-A1 Emulsion Stabilizing Agents for Drilling and Completion Fluids HALLIBURTON ENERGY SERVICES, INC. (US) 2012-10-18 US claimed
EP-2451887-A1 EMULSION STABILIZING AGENTS FOR DRILLING AND COMPLETION FLUIDS Halliburton Energy Services, Inc. (US) 2012-05-16 EP claimed
WO-2011004163-A1 EMULSION STABILIZING AGENTS FOR DRILLING AND COMPLETION FLUIDS HALLIBURTON ENERGY SERVICES, INC. (US) 2011-01-13 WO claimed
US-20110009299-A1 EMULSION STABILIZING AGENTS FOR DRILLING AND COMPLETION FLUIDS HALLIBURTON ENERGY SERVICES, INC. 2011-01-13 US claimed
EP-2451887-B1 EMULSION STABILIZING AGENTS FOR DRILLING AND COMPLETION FLUIDS HALLIBURTON ENERGY SERV INC (US) 2014-04-30 EP disclosed
US-20130137027-A1 CHARGE TRANSPORT LAYER FOR ORGANIC PHOTOCONDUCTORS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2013-05-30 US disclosed
US-20120264657-A1 Emulsion Stabilizing Agents for Drilling and Completion Fluids HALLIBURTON ENERGY SERVICES, INC. (US) 2012-10-18 US disclosed
EP-2451887-A1 EMULSION STABILIZING AGENTS FOR DRILLING AND COMPLETION FLUIDS Halliburton Energy Services, Inc. (US) 2012-05-16 EP disclosed
US-20120018716-A1 EMISSIVE SEMI-INTERPENETRATING POLYMER NETWORKS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2012-01-26 US disclosed
US-20110009299-A1 EMULSION STABILIZING AGENTS FOR DRILLING AND COMPLETION FLUIDS HALLIBURTON ENERGY SERVICES, INC. 2011-01-13 US disclosed
WO-2011004163-A1 EMULSION STABILIZING AGENTS FOR DRILLING AND COMPLETION FLUIDS HALLIBURTON ENERGY SERVICES, INC. (US) 2011-01-13 WO disclosed
US-5605970-A USING A ACRYLIC ACID, WATER MIXTURE NALCO CHEMICAL COMPANY (US) 1997-02-25 US disclosed