Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.62 |
| ▸ | CNR2 | P34972 | 10/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690931 | 0.90 | CNR1 (0.64) | CNR1CNR2KDM4EHTR3A | |
| SCHEMBL4058671 | 0.90 | CNR1 (0.64) | CNR1CNR2KDM4EHTR3A | |
| SCHEMBL4054847 | 0.89 | CNR1 (0.78) | CNR1CNR2KDM4EHTR3A | |
| SCHEMBL31052992 | 0.88 | CNR1 (0.65) | CNR1CNR2KDM4EHTR3A | |
| SCHEMBL30258887 | 0.88 | CNR1 (0.65) | CNR1CNR2KDM4EHTR3A | |
| SCHEMBL30641079 | 0.87 | CNR1 (0.67) | CNR1CNR2HTR3A | |
| SCHEMBL29993181 | 0.87 | CNR1 (0.67) | CNR1CNR2HTR3A | |
| SCHEMBL4057370 | 0.87 | CNR1 (0.47) | CNR1CNR2 | |
| SCHEMBL4050795 | 0.86 | CNR1 (0.80) | CNR1CNR2KDM4EHTR3A | |
| SCHEMBL4057247 | 0.86 | CNR1 (0.59) | CNR1CNR2KDM4EHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |