Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690695 | 1.00 | CNR1 (0.36) | CNR1CNR2SSTR4SCN9APOLB | |
| SCHEMBL13690731 | 0.90 | CNR1 (0.37) | CNR1CNR2SSTR4POLB | |
| SCHEMBL13690715 | 0.89 | CNR1 (0.38) | CNR1CNR2SSTR4POLBCFD | |
| SCHEMBL13691083 | 0.88 | CNR1 (0.38) | CNR1CNR2 | |
| SCHEMBL4049942 | 0.88 | CNR1 (0.38) | CNR1CNR2 | |
| SCHEMBL4054062 | 0.88 | CNR1 (0.38) | CNR1CNR2 | |
| SCHEMBL13691121 | 0.88 | CNR1 (0.37) | CNR1CNR2SSTR4POLBCFD | |
| SCHEMBL4049667 | 0.88 | CNR1 (0.41) | CNR1CNR2SSTR4POLBCFD | |
| SCHEMBL13690727 | 0.88 | CNR1 (0.36) | CNR1CNR2SSTR4SCN9A | |
| SCHEMBL13691350 | 0.88 | CNR1 (0.36) | CNR1CNR2SSTR4SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |