SCHEMBL4049667

SCHEMBL4049667

CC(C)(C)[C@H](NC(=O)c1nn(CC2CC(F)(F)C2)c2c(F)cccc12)C(=O)NCC(N)=O

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 7/20 0.41
CNR2 P34972 4/20 0.40
SSTR4 P31391 1/20 0.33
CFD P00746 7/20 0.33
POLB P06746 1/20 0.32
GPR119 Q8TDV5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4050200 0.92 CNR1 (0.43) CNR1CNR2CFD
SCHEMBL13690712 0.91 CNR1 (0.49) CNR1CNR2SSTR4POLB
SCHEMBL13691121 0.90 CNR1 (0.37) CNR1CNR2SSTR4CFDPOLB
SCHEMBL13690731 0.90 CNR1 (0.37) CNR1CNR2SSTR4POLB
SCHEMBL4053936 0.89 CNR1 (0.51) CNR1CNR2SSTR4CFD
SCHEMBL13690985 0.89 CNR1 (0.51) CNR1CNR2SSTR4CFD
SCHEMBL13691322 0.88 CNR1 (0.36) CNR1CNR2SSTR4POLB
SCHEMBL13690695 0.88 CNR1 (0.36) CNR1CNR2SSTR4CFDPOLB
SCHEMBL4049690 0.88 CNR1 (0.36) CNR1CNR2SSTR4CFDPOLB
SCHEMBL4051582 0.88 CNR1 (0.42) CNR1CNR2CFD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009106980-A2 INDAZOLE DERIVATIVES PFIZER INC. (US) 2009-09-03 WO disclosed