Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.43 |
| ▸ | CNR1 | P21554 | 9/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690501 | 1.00 | CNR2 (0.43) | CNR2CNR1CTSVCTSLCTSB | |
| SCHEMBL4050243 | 0.88 | CNR1 (0.49) | CNR2CNR1CTSVCTSLCTSB | |
| SCHEMBL4052822 | 0.87 | CNR1 (0.60) | CNR2CNR1CTSVCTSLCTSB | |
| SCHEMBL4049686 | 0.82 | CNR1 (0.45) | CNR2CNR1CREBBPHTR3A | |
| SCHEMBL4055740 | 0.82 | CNR1 (0.49) | CNR2CNR1CTSVCTSLCTSB | |
| SCHEMBL4059141 | 0.81 | CNR1 (0.53) | CNR2CNR1KDM4CCREBBPHTR3A | |
| SCHEMBL4057565 | 0.81 | CNR1 (0.43) | CNR2CNR1HTR3A | |
| SCHEMBL13690527 | 0.80 | CNR1 (0.47) | CNR2CNR1CTSLCTSBCTSS | |
| SCHEMBL4055098 | 0.80 | CNR2 (0.47) | CNR2CNR1GHSRHTR3A | |
| SCHEMBL13690903 | 0.80 | CNR2 (0.47) | CNR2CNR1GHSRHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |