Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | HTR3A | P46098 | 5/20 | 0.40 |
| ▸ | MMP2 | P08253 | 8/20 | 0.36 |
| ▸ | MMP3 | P08254 | 4/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4049686 | 0.97 | CNR1 (0.45) | CNR1CNR2HTR3AMMP2MMP3 | |
| SCHEMBL4051379 | 0.91 | CNR1 (0.43) | CNR1CNR2HTR3AMMP2MMP3 | |
| SCHEMBL13690916 | 0.90 | HTR3A (0.48) | CNR1CNR2HTR3AMMP2MMP3 | |
| SCHEMBL13690563 | 0.89 | CNR1 (0.56) | CNR1CNR2HTR3AMMP2MMP3 | |
| SCHEMBL4056242 | 0.89 | CNR1 (0.56) | CNR1CNR2HTR3AMMP2MMP3 | |
| SCHEMBL4049656 | 0.88 | CNR1 (0.44) | CNR1CNR2HTR3A | |
| SCHEMBL4053731 | 0.88 | CNR1 (0.44) | CNR1CNR2HTR3A | |
| SCHEMBL4050243 | 0.85 | CNR1 (0.49) | CNR1CNR2 | |
| SCHEMBL4052822 | 0.85 | CNR1 (0.60) | CNR1CNR2 | |
| SCHEMBL4055740 | 0.84 | CNR1 (0.49) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |