Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746194 | 0.90 | KMT2A (0.53) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL9309031 | 0.86 | KMT2A (0.61) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL31314673 | 0.84 | KMT2A (0.45) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL27855048 | 0.83 | KMT2A (0.47) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL8746110 | 0.83 | KMT2A (0.50) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL18050608 | 0.83 | KMT2A (0.50) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL8746236 | 0.81 | KMT2A (0.49) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL71841 | 0.79 | KMT2A (0.53) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL7619550 | 0.78 | KMT2A (0.57) | KMT2ACA1CA2MMP1MMP2 | |
| SCHEMBL3620173 | 0.77 | KMT2A (0.52) | KMT2ACA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170326114-A1 | COGNITIVE FUNCTION | GEORGETOWN UNIVERSITY | 2017-11-16 | — | — | US | disclosed |
| US-20160000762-A1 | IMPROVING COGNITIVE FUNCTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-07 | — | — | US | disclosed |
| WO-2014134287-A1 | IMPROVING COGNITIVE FUNCTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-09-04 | — | — | WO | disclosed |
| WO-2009114385-A1 | LYOTROPIC CHROMOPHORIC COMPOUNDS, LIQUID CRYSTAL SYSTEMS AND OPTICALLY ANISOTROPIC FILMS | NITTO DENKO CORPORATION (JP) | 2009-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170326114-A1 | COGNITIVE FUNCTION | CHAT, FABP7, BCHE | KMT2A 1036/4885CA1 173/4885CA2 1807/4885 |
| US-20160000762-A1 | IMPROVING COGNITIVE FUNCTION | CHAT, FABP7, GRIN2A | KMT2A 1424/4885CA1 338/4885CA2 1942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.