SCHEMBL9309031

SCHEMBL9309031

O=S(=O)(Cc1ccccc1)OCCOS(=O)(=O)Cc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.61
CA2 P00918 5/20 0.52
CA1 P00915 4/20 0.52
CA9 Q16790 3/20 0.52
PRSS1 P07477 3/20 0.52
PRSS2 P07478 3/20 0.52
PRSS3 P35030 3/20 0.52
FAAH O00519 1/20 0.52
ELANE P08246 1/20 0.52
PRTN3 P24158 1/20 0.52
CA5A P35218 1/20 0.52
HTT P42858 1/20 0.47
MMP1 P03956 1/20 0.47
MMP2 P08253 1/20 0.47
MMP9 P14780 1/20 0.47
MMP8 P22894 1/20 0.47
MMP13 P45452 1/20 0.47
F2 P00734 2/20 0.42
HSP90AA1 P07900 1/20 0.42
HPGD P15428 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7619550 0.91 KMT2A (0.57) KMT2ACA2CA1CA9PRSS1
SCHEMBL3620173 0.90 KMT2A (0.52) KMT2ACA2CA1CA9PRSS1
SCHEMBL6912270 0.90 CA1 (0.63) KMT2ACA2CA1CA9PRSS1
SCHEMBL18050608 0.89 KMT2A (0.50) KMT2ACA2CA1CA9PRSS1
SCHEMBL2383968 0.88 KMT2A (0.53) KMT2ACA2CA1CA9PRSS1
SCHEMBL2762566 0.88 KMT2A (0.53) KMT2ACA2CA1CA9PRSS1
SCHEMBL29482067 0.88 KMT2A (0.53) KMT2ACA2CA1CA9PRSS1
SCHEMBL8746194 0.88 KMT2A (0.53) KMT2ACA2CA1CA9PRSS1
SCHEMBL71841 0.88 KMT2A (0.53) KMT2ACA2CA1CA9PRSS1
SCHEMBL28223632 0.88 KMT2A (0.53) KMT2ACA2CA1CA9PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250049966-A1 SMALL MOLECULE TRACER FOR IMAGING ALPHA-SYNUCLEIN AGGREGATES FUDAN UNIVERSITY (CN) 2025-02-13 US disclosed
WO-2023109745-A1 SMALL-MOLECULE PROBE FOR IMAGING OF α-SYNUCLEIN AGGREGATE 复旦大学 2023-06-22 WO disclosed
WO-2023104148-A1 SMALL MOLECULE PROBE BINDING TO α-SYNUCLEIN AGGREGATE AND APPLICATION THEREOF 复旦大学 2023-06-15 WO disclosed
CN-115286616-A Tetrahydroisoquinoline and isoindoline compound capable of binding sigma-2 receptor, preparation method and application thereof 北京师范大学 2022-11-04 CN disclosed
EP-2602856-B1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY USING SAME WAKO PURE CHEM IND LTD (JP) 2017-02-22 EP disclosed
EP-2602856-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY USING SAME Wako Pure Chemical Industries, Ltd. (JP) 2013-06-12 EP disclosed
US-20130130128-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY USING SAME WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2013-05-23 US disclosed
US-20130130128-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY USING SAME WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2013-05-23 US disclosed
US-5371126-A Quenching optical brighteners; an acid addition salt or quartenization product of a cyclic amidine, polyethyleneimine and optionally an acid; cleaning and flushing SANDOZ LTD. (CH) 1994-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250049966-A1 SMALL MOLECULE TRACER FOR IMAGING ALPHA-SYNUCLEIN AGGREGATES SNCA, PARK7, GDI1 KMT2A 4424/4885CA2 4810/4885CA1 4648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.