Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1443663 | 0.90 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL4055273 | 0.89 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL4054016 | 0.89 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL1239921 | 0.89 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL10497693 | 0.89 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL1164373 | 0.89 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL585375 | 0.89 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL1958537 | 0.89 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL2041458 | 0.89 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL1864244 | 0.89 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |