⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240756 | 0.84 | — | — | |
| SCHEMBL4058802 | 0.78 | ALDH1A1 (0.30) | — | |
| SCHEMBL20024603 | 0.71 | — | — | |
| SCHEMBL479259 | 0.71 | — | — | |
| SCHEMBL12249019 | 0.70 | — | — | |
| SCHEMBL11201242 | 0.70 | — | — | |
| SCHEMBL8343366 | 0.68 | PLA2G1B (0.35) | — | |
| SCHEMBL10457577 | 0.68 | — | — | |
| SCHEMBL10457578 | 0.68 | — | — | |
| SCHEMBL407912 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917290-B1 | POLYAMMONIUM-POLYSILOXANE COPOLYMERS | MOMENTIVE PERFORMANCE MAT INC (DE) | 2013-06-26 | — | — | EP | disclosed |
| US-8362185-B2 | Polyammonium/polysiloxane copolymers | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2013-01-29 | — | — | US | disclosed |
| US-20090142293-A1 | Polyammonium/Polysiloxane Copolymers | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2009-06-04 | — | — | US | disclosed |