Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 5/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690984 | 1.00 | CNR1 (0.50) | CNR1KDM4CCNR2HTR3AMMP2 | |
| SCHEMBL13691265 | 0.93 | CNR1 (0.50) | CNR1KDM4CCNR2HTR3AMMP2 | |
| SCHEMBL4053108 | 0.93 | CNR1 (0.50) | CNR1KDM4CCNR2HTR3AMMP2 | |
| SCHEMBL4059913 | 0.92 | ROCK1 (0.43) | CNR1KDM4CCNR2HTR3AROCK1 | |
| SCHEMBL13690981 | 0.92 | ROCK1 (0.43) | CNR1KDM4CCNR2HTR3AROCK1 | |
| SCHEMBL4049364 | 0.91 | CNR1 (0.42) | CNR1KDM4CCNR2HTR3AHTR2A | |
| SCHEMBL4050445 | 0.89 | CNR1 (0.59) | CNR1KDM4CCNR2HTR2AHTR2C | |
| SCHEMBL13691249 | 0.89 | CNR1 (0.59) | CNR1KDM4CCNR2HTR2AHTR2C | |
| SCHEMBL13690556 | 0.88 | CNR1 (0.49) | CNR1CNR2HTR3AMMP2MMP3 | |
| SCHEMBL4051688 | 0.88 | CNR1 (0.49) | CNR1KDM4CCNR2HTR3AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |