Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 6/20 | 0.41 |
| ▸ | CNR2 | P34972 | 7/20 | 0.41 |
| ▸ | HTR3A | P46098 | 4/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690981 | 1.00 | ROCK1 (0.43) | ROCK1CNR1CNR2HTR3AHTR4 | |
| SCHEMBL13690608 | 0.93 | ROCK1 (0.43) | ROCK1CNR1CNR2HTR3AHTR4 | |
| SCHEMBL4050249 | 0.92 | CNR1 (0.50) | ROCK1CNR1CNR2HTR3AKDM4C | |
| SCHEMBL13690984 | 0.92 | CNR1 (0.50) | ROCK1CNR1CNR2HTR3AKDM4C | |
| SCHEMBL13690926 | 0.91 | CNR1 (0.42) | CNR1CNR2HTR3AHTR4KDM4C | |
| SCHEMBL4051939 | 0.91 | CNR1 (0.42) | CNR1CNR2HTR3AHTR4KDM4C | |
| SCHEMBL4049364 | 0.89 | CNR1 (0.42) | ROCK1CNR1CNR2HTR3AHTR4 | |
| SCHEMBL4055909 | 0.89 | CNR1 (0.49) | ROCK1CNR1CNR2HTR3AKDM4C | |
| SCHEMBL4057153 | 0.89 | ROCK1 (0.47) | ROCK1CNR1CNR2HTR3AHTR4 | |
| SCHEMBL4048374 | 0.89 | ROCK1 (0.44) | ROCK1CNR1CNR2HTR3AHTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |