Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 16/20 | 0.37 |
| ▸ | IL1B | P01584 | 15/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691048 | 1.00 | CNR1 (0.38) | CNR1P2RX7IL1BCNR2 | |
| SCHEMBL13691049 | 0.95 | CNR1 (0.39) | CNR1P2RX7IL1BCNR2 | |
| SCHEMBL4059287 | 0.95 | CNR1 (0.39) | CNR1P2RX7IL1BCNR2 | |
| SCHEMBL13690998 | 0.92 | CNR1 (0.39) | CNR1P2RX7IL1BCNR2 | |
| SCHEMBL4050180 | 0.92 | CNR1 (0.39) | CNR1P2RX7IL1BCNR2 | |
| SCHEMBL13690708 | 0.90 | CNR1 (0.40) | CNR1P2RX7IL1BCNR2 | |
| SCHEMBL13691051 | 0.89 | CNR1 (0.42) | CNR1P2RX7IL1BCNR2 | |
| SCHEMBL4056167 | 0.89 | CNR1 (0.42) | CNR1P2RX7IL1BCNR2 | |
| SCHEMBL4059054 | 0.88 | CNR1 (0.51) | CNR1CNR2 | |
| SCHEMBL13691013 | 0.88 | CNR1 (0.51) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |