Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 14/20 | 0.38 |
| ▸ | IL1B | P01584 | 13/20 | 0.38 |
| ▸ | CFD | P00746 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691051 | 1.00 | CNR1 (0.42) | CNR1CNR2P2RX7IL1BCFD | |
| SCHEMBL13690708 | 0.93 | CNR1 (0.40) | CNR1CNR2P2RX7IL1B | |
| SCHEMBL4050200 | 0.91 | CNR1 (0.43) | CNR1CNR2P2RX7IL1BCFD | |
| SCHEMBL13691049 | 0.91 | CNR1 (0.39) | CNR1CNR2P2RX7IL1B | |
| SCHEMBL4059287 | 0.91 | CNR1 (0.39) | CNR1CNR2P2RX7IL1B | |
| SCHEMBL13691048 | 0.89 | CNR1 (0.38) | CNR1CNR2P2RX7IL1B | |
| SCHEMBL4050609 | 0.89 | CNR1 (0.38) | CNR1CNR2P2RX7IL1B | |
| SCHEMBL13691310 | 0.89 | CNR1 (0.40) | CNR1CNR2P2RX7IL1BCFD | |
| SCHEMBL13690975 | 0.88 | CNR1 (0.56) | CNR1CNR2CFD | |
| SCHEMBL13691117 | 0.87 | PTGER4 (0.41) | CNR1P2RX7IL1BCFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |