Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10349749 | 0.87 | PARP10 (0.71) | PARP10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5609808 | 0.85 | NPC1 (0.64) | PARP10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9034998 | 0.82 | NPC1 (0.54) | PARP10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2516394 | 0.81 | PARP10 (0.68) | PARP10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL15249121 | 0.79 | PARP10 (0.61) | PARP10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7252796 | 0.79 | KDM4E (0.41) | PARP10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL20024703 | 0.78 | NPC1 (0.61) | PARP10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL15249111 | 0.77 | NPC1 (0.63) | PARP10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL123733 | 0.77 | FFAR1 (0.62) | PARP10NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7247688 | 0.77 | LOXL2 (0.50) | LMNASMN1; SMN2NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365328-B1 | Pyridine derivatives | ZENECA LTD (GB) | 1996-04-03 | — | — | EP | claimed |
| US-5053415-A | Antiischemic, antiinflammatory, antiarthritic agents, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-01 | — | — | US | claimed |
| EP-0365328-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1990-04-25 | — | — | EP | claimed |
| CN-110249004-A | Polyimide precursor composition | 东京应化工业株式会社 | 2019-09-17 | — | — | CN | disclosed |
| CN-108389512-A | The manufacturing method of laminated body, flexible devices and laminated body | 东京应化工业株式会社 | 2018-08-10 | — | — | CN | disclosed |
| CN-108387954-A | The manufacturing method of laminated body, flexible devices and laminated body | 东京应化工业株式会社 | 2018-08-10 | — | — | CN | disclosed |
| CN-107429059-A | ENERGY-SENSITIVE RESIN COMPOSITION | 东京应化工业株式会社 | 2017-12-01 | — | — | CN | disclosed |
| EP-1397137-B1 | HYDANTION DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | BRISTOL MYERS SQUIBB CO (US) | 2009-10-14 | — | — | EP | disclosed |
| US-7482372-B2 | Hydantoins and related heterocycles as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme (TACE) | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-01-27 | — | — | US | disclosed |
| EP-1558581-A4 | TRIAZOLONE AND TRIAZOLETHIONE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2007-07-25 | — | — | EP | disclosed |
| US-7074810-B2 | Triazolone and triazolethione derivatives as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-11 | — | — | US | disclosed |
| EP-0831796-A1 | METHOD FOR REDUCING OR PREVENTING POST-SURGICAL ADHESION FORMATION USING 5-LIPOXYGENASE INHIBITORS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1998004555-A1 | NON-SYMMETRICAL BIS-HETEROARYLMETHOXYPHENYLALKYL CARBOXYLATES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1998-02-05 | — | — | WO | disclosed |
| US-5668150-A | ANTIALLERGY, ANTIINFLAMMATORY | ABBOTT LABORATORIES (US) | 1997-09-16 | — | — | US | disclosed |
| WO-1996040090-A1 | METHOD FOR REDUCING OR PREVENTING POST-SURGICAL ADHESION FORMATION USING 5-LIPOXYGENASE INHIBITORS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0365328-B1 | Pyridine derivatives | ZENECA LTD (GB) | 1996-04-03 | — | — | EP | disclosed |
| US-5358955-A | Antiinflammatory agents | ABBOTT LABORATORIES (US) | 1994-10-25 | — | — | US | disclosed |
| US-5053415-A | Antiischemic, antiinflammatory, antiarthritic agents, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-01 | — | — | US | disclosed |
| EP-0365328-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1990-04-25 | — | — | EP | disclosed |
| US-4035190-A | 2-ISOXAZOLIN-3-HETEROCYCLIC-SUBSTITUTED | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1977-07-12 | — | — | US | disclosed |