Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | PTGES | O14684 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MYOC | Q99972 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3836117 | 0.86 | GAA (0.78) | GAAPTGESKMT2AMEN1ALDH1A1 | |
| SCHEMBL7621088 | 0.85 | GAA (1.00) | GAAPTGESKMT2AMEN1ALDH1A1 | |
| SCHEMBL11180078 | 0.81 | GAA (0.69) | GAAPTGESKMT2AMEN1ALDH1A1 | |
| SCHEMBL6815793 | 0.79 | KMT2A (0.59) | GAAPTGESKMT2AMEN1ALDH1A1 | |
| SCHEMBL27491602 | 0.79 | ALDH1A1 (0.70) | GAAPTGESKMT2AMEN1ALDH1A1 | |
| SCHEMBL2231790 | 0.78 | GAA (0.57) | GAAPTGESKMT2AMEN1ALDH1A1 | |
| SCHEMBL7616591 | 0.78 | GAA (0.69) | GAAPTGESKMT2AMEN1ALDH1A1 | |
| SCHEMBL27898872 | 0.78 | GAA (0.65) | GAAPTGESKMT2AMEN1ALDH1A1 | |
| SCHEMBL8848976 | 0.77 | KMT2A (0.71) | GAAKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL642700 | 0.77 | KMT2A (0.81) | GAAKMT2AMEN1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |