Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 10/20 | 0.32 |
| ▸ | CASP2 | P42575 | 10/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044235 | 0.92 | CTSK (0.35) | DPP4DPP8DPP9CTSK | |
| SCHEMBL4047635 | 0.90 | PREP (0.38) | CTSKACE2 | |
| SCHEMBL4046603 | 0.89 | CTSK (0.39) | CTSK | |
| SCHEMBL4054795 | 0.88 | CTSK (0.39) | CTSK | |
| SCHEMBL4047114 | 0.87 | CTSK (0.48) | CTSKACE2 | |
| SCHEMBL4045682 | 0.87 | CTSK (0.35) | CTSK | |
| SCHEMBL4048903 | 0.86 | CTSK (0.40) | CTSK | |
| SCHEMBL4048659 | 0.86 | CTSK (0.35) | DPP4CTSK | |
| SCHEMBL4040440 | 0.86 | CTSK (0.38) | CTSK | |
| SCHEMBL4046795 | 0.85 | CTSK (0.41) | DPP4CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |