Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057473 | 1.00 | HMGCR (0.42) | HMGCRFAAHTRPV1ALDH1A1TSHR | |
| SCHEMBL10689323 | 0.98 | HMGCR (0.45) | HMGCRFAAHTRPV1GMNNUSP2 | |
| SCHEMBL14714699 | 0.76 | — | — | |
| SCHEMBL16633594 | 0.74 | HMGCR (0.53) | HMGCRFAAHTRPV1ALDH1A1TSHR | |
| SCHEMBL16633593 | 0.74 | HMGCR (0.53) | HMGCRFAAHTRPV1ALDH1A1TSHR | |
| SCHEMBL21670626 | 0.72 | FAAH (0.45) | FAAHTRPV1GMNNUSP2LMNA | |
| SCHEMBL14759818 | 0.70 | FAAH (0.52) | FAAHTRPV1TSHRGMNNUSP2 | |
| SCHEMBL14759955 | 0.70 | FAAH (0.52) | FAAHTRPV1TSHRGMNNUSP2 | |
| SCHEMBL14760009 | 0.70 | FAAH (0.52) | FAAHTRPV1TSHRGMNNUSP2 | |
| SCHEMBL14759666 | 0.70 | FAAH (0.52) | FAAHTRPV1TSHRGMNNUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111830-A1 | CONJUGATED UNSATURATED COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2009-09-17 | — | — | WO | disclosed |