Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.80 |
| ▸ | CNR2 | P34972 | 4/20 | 0.52 |
| ▸ | CFD | P00746 | 2/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052482 | 0.89 | CNR1 (1.00) | CNR1CNR2CFDHTR4KDM4E | |
| SCHEMBL29706145 | 0.89 | CNR1 (1.00) | CNR1CNR2CFDHTR4KDM4E | |
| SCHEMBL13691214 | 0.89 | CNR1 (1.00) | CNR1CNR2CFDHTR4KDM4E | |
| SCHEMBL13691313 | 0.89 | CNR1 (0.67) | CNR1CNR2CFDHTR4KDM4E | |
| SCHEMBL4051743 | 0.89 | CNR1 (0.67) | CNR1CNR2CFDHTR4KDM4E | |
| SCHEMBL4054945 | 0.89 | CNR1 (0.67) | CNR1CNR2CFDHTR4KDM4E | |
| SCHEMBL4050776 | 0.88 | CNR1 (0.75) | CNR1CNR2CFDHTR4KDM4E | |
| SCHEMBL13690864 | 0.88 | CNR1 (0.69) | CNR1CNR2CFDHTR4KDM4E | |
| SCHEMBL13690891 | 0.87 | CNR1 (0.73) | CNR1CNR2CFDHTR4KDM4E | |
| SCHEMBL4560432 | 0.86 | CNR1 (0.83) | CNR1CNR2HTR4KDM4EACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |