SCHEMBL29706145

SCHEMBL29706145

CC(C)[C@H](NC(=O)c1nn(CC2CCCCC2)c2ccccc12)C(N)=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 9/20 1.00
CNR2 P34972 5/20 0.66
KDM4E B2RXH2 1/20 0.46
ACHE P22303 1/20 0.45
HTR4 Q13639 3/20 0.44
HTR3A P46098 4/20 0.44
CFD P00746 1/20 0.44
ROCK2 O75116 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4052482 1.00 CNR1 (1.00) CNR1CNR2KDM4EACHEHTR4
SCHEMBL13691214 1.00 CNR1 (1.00) CNR1CNR2KDM4EACHEHTR4
SCHEMBL4560432 0.91 CNR1 (0.83) CNR1CNR2KDM4EACHEHTR4
SCHEMBL13690513 0.90 CNR1 (0.82) CNR1CNR2HTR4HTR3AROCK2
SCHEMBL30641101 0.89 CNR1 (0.80) CNR1CNR2KDM4EACHEHTR4
SCHEMBL4051085 0.89 CNR1 (0.80) CNR1CNR2KDM4EACHEHTR4
SCHEMBL4053063 0.87 CNR1 (0.77) CNR1CNR2KDM4EACHEHTR4
SCHEMBL30473233 0.87 CNR1 (0.77) CNR1CNR2KDM4EACHEHTR4
SCHEMBL29993194 0.87 CNR1 (0.77) CNR1CNR2KDM4EACHEHTR4
SCHEMBL4049660 0.86 CNR1 (0.76) CNR1CNR2KDM4EACHEHTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US claimed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP claimed
EP-3664795-B1 CANNABIS AND DERIVATIVES THEREOF FOR THE TREATMENT OF PAIN AND INFLAMMATION RELATED WITH DENTAL PULP AND BONE REGENERATION RELATED TO DENTAL JAW BONE DEFECTS CANNIBITE BVBA (BE) 2024-06-19 EP claimed
CN-118063385-A Hapten for synthesizing cannabinoid ADB-BUTINACA, monoclonal antibody and application thereof 中国药科大学 2024-05-24 CN claimed
WO-2024107445-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES, INC. (US) 2024-05-23 WO claimed
CN-117805259-A Method for rapidly analyzing 87 synthetic cannabinoids and metabolites thereof in urine after enzymolysis 司法鉴定科学研究院 2024-04-02 CN claimed
CN-114942239-B Composition, kit and method for rapidly detecting synthetic cannabinoid in tobacco tar 合肥市公安局刑事警察支队 2024-02-06 CN claimed
CN-113419018-B Pretreatment method of incense sample and method for detecting various cannabinoids in incense smoke 福州海关技术中心 2022-06-17 CN claimed
US-12637447-B2 Carboxylic acid, acyl sulfonamide and acyl sulfamide-derivatized bicyclic aza-heteroaromatics as selective mcl-1 inhibitors and as dual mcl-1/bcl-2 inhibitors UNIVERSITY OF MARYLAND, BALTIMORE (US) 2026-05-26 US disclosed
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US disclosed
EP-4646477-A2 METHODS AND COMPOSITIONS FOR DISPLAYING PEPTIDE LIBRARIES Board of Regents, The University of Texas System (US) 2025-11-12 EP disclosed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP disclosed
US-20250241933-A1 METHODS OF TREATING SLEEP APNEA WITH A COMBINATION OF A CANNABINOID AND A CARBONIC ANHYDRASE INHIBITOR APNIMED, INC. (DELAWARE) 2025-07-31 US disclosed
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES Ananda Scientific, Inc. (US) 2025-06-19 US disclosed
CN-115876920-A Method for analyzing multiple novel psychoactive substances in food by gas chromatography-mass spectrometry 三明海关综合技术服务中心 2023-03-31 CN disclosed
US-11612581-B2 Cannabis and derivatives thereof for the treatment of pain and inflammation related with dental pulp and bone regeneration related to dental jaw bone defects CANNIBITE BVBA 2023-03-28 US disclosed
US-20220406587-A1 MASS SPECTROMETRY METHODS AND RELATED MATERIALS THE TRUSTEES OF INDIANA UNIVERSITY 2022-12-22 US disclosed
WO-2022221613-A1 COMBINATION OF A NOREPINEPHRINE REUPTAKE INHIBITOR AND A CANNABINOID FOR USE IN TREATING SLEEP APNEA APNIMED, INC. (DELAWARE) (US) 2022-10-20 WO disclosed
WO-2022217147-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES ROSENFELD MARK J (US) 2022-10-13 WO disclosed
CN-113419018-B Pretreatment method of incense sample and method for detecting various cannabinoids in incense smoke 福州海关技术中心 2022-06-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637447-B2 Carboxylic acid, acyl sulfonamide and acyl sulfamide-derivatized bicyclic aza-heteroaromatics as selective mcl-1 inhibitors and as dual mcl-1/bcl-2 inhibitors MCL1, BCL2L1, BCL2L2 CNR1 85/4885CNR2 130/4885KDM4E 2932/4885
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES PDE9A, PDE3A, PDE2A CNR1 221/4885CNR2 204/4885KDM4E 1355/4885
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES CNR2, CNR1, FAAH CNR1 2/4885CNR2 1/4885KDM4E 1623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.