Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.52 |
| ▸ | CTSS | P25774 | 5/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038744 | 0.91 | CTSK (0.56) | CTSKCTSSDPP4PREPHPGDS | |
| SCHEMBL4046306 | 0.90 | CTSK (0.55) | CTSKCTSSDPP4PREPHPGDS | |
| SCHEMBL4044011 | 0.86 | CTSK (0.57) | CTSKCTSSDPP4PREPHPGDS | |
| SCHEMBL4042324 | 0.86 | CTSK (0.57) | CTSKCTSSDPP4PREPCTSB | |
| SCHEMBL4043125 | 0.85 | CTSK (0.55) | CTSKCTSSDPP4PREPHPGDS | |
| SCHEMBL4043316 | 0.85 | CTSK (0.55) | CTSKCTSSDPP4PREPHPGDS | |
| SCHEMBL4040919 | 0.85 | CTSK (0.60) | CTSKCTSSDPP4PREPHPGDS | |
| SCHEMBL4046198 | 0.85 | CTSK (0.56) | CTSKCTSSDPP4PREPHPGDS | |
| SCHEMBL4042562 | 0.85 | CTSK (0.58) | CTSKCTSSHPGDSCTSBCTSL | |
| SCHEMBL4042616 | 0.85 | CTSK (0.59) | CTSKCTSSHPGDSCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |