Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10664497 | 0.89 | EPHX1 (0.41) | — | |
| Acetic Acid SCHEMBL1287799 | 0.88 | — | — | |
| SCHEMBL9502832 | 0.85 | — | — | |
| Bicarbonate SCHEMBL10617200 | 0.85 | — | — | |
| Acetic Acid SCHEMBL2803174 | 0.85 | FFAR3 (0.50) | — | |
| Carbamic Acid SCHEMBL11215146 | 0.85 | — | — | |
| Bicarbonate SCHEMBL8034269 | 0.84 | EPHX2 (0.40) | — | |
| Methylcyclopentane SCHEMBL8746944 | 0.82 | EPHX1 (0.46) | — | |
| Bicarbonate SCHEMBL1132251 | 0.82 | EPHX1 (0.37) | — | |
| Bicarbonate SCHEMBL8796364 | 0.82 | EPHX1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635567-B1 | INDOLE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2015-10-28 | — | — | EP | claimed |
| EP-0052473-B1 | N-SUBSTITUTED PHENYL-1-METHYLCYCLOPROPANECARBOXAMIDES, THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-08-22 | — | — | EP | claimed |
| EP-0037375-A1 | Insecticidal-vapours emitting device | Airwick AG (CH) | 1981-10-07 | — | — | EP | claimed |
| EP-3515919-A1 | N3-CYCLICALLY SUBSTITUTED THIENOURACILES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2019-07-31 | — | — | EP | disclosed |
| WO-2018054846-A1 | N3-CYCLICALLY SUBSTITUTED THIENOURACILES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | WO | disclosed |
| EP-2018387-A1 | THIAZOLYLDIHYDROINDAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007115933-A1 | THIAZOLYLDIHYDROINDAZOLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |
| EP-1107946-A2 | CYCLOALKYL CARBOXYLIC ACID AMIDES, THEIR PRODUCTION AND THEIR USE AS FUNGICIDES IN AGRICULTURE | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-20 | — | — | EP | disclosed |
| EP-0775125-B1 | SACCHARINE DERIVATIVES AND THEIR USE AS HERBICIDES | BASF AG (DE) | 2000-12-27 | — | — | EP | disclosed |
| EP-0810998-B1 | PHENYL DIKETONE DERIVATIVES AS HERBICIDES | BASF AG (DE) | 2000-04-26 | — | — | EP | disclosed |
| US-6043236-A | Estrogens | ASTRA AKTIEBOLAG (SE) | 2000-03-28 | — | — | US | disclosed |
| WO-1986006369-A1 | ANTI-MICROBIAL NITRILE AND ITS PRODUCTION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1986-11-06 | — | — | WO | disclosed |
| EP-0186043-A1 | Milbemycin derivatives with pesticide properties | CIBA-GEIGY AG (CH) | 1986-07-02 | — | — | EP | disclosed |
| EP-0168608-A2 | Substituted carboxylic-acid anilides | BAYER AG (DE) | 1986-01-22 | — | — | EP | disclosed |
| EP-0157088-A1 | Process for the preparation of polyisocyanates having a biuret structure | BAYER AG (DE) | 1985-10-09 | — | — | EP | disclosed |
| EP-0150769-A2 | Process for the production of polyisocyanates with a biuret structure | BAYER AG (DE) | 1985-08-07 | — | — | EP | disclosed |
| EP-0089011-B1 | PROCESS FOR THE PREPARATION OF 5-OXONITRILES | Degussa Aktiengesellschaft (DE) | 1985-07-10 | — | — | EP | disclosed |
| EP-0043950-B1 | 1-METHYL-2-CHLORO-CYCLOPROPANECARBOXYLIC ACID AND ITS ESTERS, PROCESS FOR THEIR PREPARATION | Degussa Aktiengesellschaft (DE) | 1984-09-05 | — | — | EP | disclosed |
| EP-0089011-A1 | Process for the preparation of 5-oxonitriles | Degussa Aktiengesellschaft (DE) | 1983-09-21 | — | — | EP | disclosed |
| EP-0043950-A1 | 1-Methyl-2-chloro-cyclopropanecarboxylic acid and its esters, process for their preparation | Degussa Aktiengesellschaft (DE) | 1982-01-20 | — | — | EP | disclosed |