Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.79 |
| ▸ | RAB9A | P51151 | 1/20 | 0.79 |
| ▸ | MYC | P01106 | 1/20 | 0.79 |
| ▸ | MAX | P61244 | 1/20 | 0.79 |
| ▸ | MMP3 | P08254 | 1/20 | 0.78 |
| ▸ | MMP13 | P45452 | 1/20 | 0.78 |
| ▸ | CTSD | P07339 | 3/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.67 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.63 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.63 |
| ▸ | CLK1 | P49759 | 1/20 | 0.63 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.63 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.63 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051343 | 1.00 | NPC1 (0.79) | NPC1RAB9AMYCMAXMMP3 | |
| SCHEMBL4049595 | 0.91 | MMP3 (0.75) | NPC1RAB9AMYCMAXMMP3 | |
| SCHEMBL4049596 | 0.91 | MMP3 (0.75) | NPC1RAB9AMYCMAXMMP3 | |
| SCHEMBL7974643 | 0.91 | MMP3 (0.75) | NPC1RAB9AMYCMAXMMP3 | |
| SCHEMBL7975038 | 0.91 | MMP3 (0.75) | NPC1RAB9AMYCMAXMMP3 | |
| SCHEMBL7975036 | 0.91 | MMP3 (0.75) | NPC1RAB9AMYCMAXMMP3 | |
| SCHEMBL4056380 | 0.91 | HPGD (0.82) | NPC1RAB9AMYCMAXMMP3 | |
| SCHEMBL4050763 | 0.91 | HPGD (0.82) | NPC1RAB9AMYCMAXMMP3 | |
| SCHEMBL4050762 | 0.91 | HPGD (0.82) | NPC1RAB9AMYCMAXMMP3 | |
| SCHEMBL4056382 | 0.91 | HPGD (0.82) | NPC1RAB9AMYCMAXMMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |