Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.77 |
| ▸ | CNR2 | P34972 | 8/20 | 0.77 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053457 | 0.97 | CNR1 (0.79) | CNR1CNR2CAPN1CTSBHTR3A | |
| SCHEMBL4052275 | 0.89 | CNR1 (0.65) | CNR1CNR2CTSBHPGDSCTSL | |
| SCHEMBL30446074 | 0.87 | CNR1 (1.00) | CNR1CNR2CAPN1CTSBHTR3A | |
| SCHEMBL4051236 | 0.84 | CNR1 (0.56) | CNR1CNR2HTR3AUSP30PTGER4 | |
| SCHEMBL4049649 | 0.82 | CNR1 (0.80) | CNR1CNR2HTR3A | |
| SCHEMBL4054847 | 0.82 | CNR1 (0.78) | CNR1CNR2HTR3A | |
| SCHEMBL4059848 | 0.81 | CNR1 (0.56) | CNR1CNR2HTR3AUSP30PTGER4 | |
| SCHEMBL6113989 | 0.80 | PARP1 (0.56) | CNR1CNR2HTR3A | |
| SCHEMBL13691268 | 0.79 | CNR1 (0.53) | CNR1CNR2HTR3AUSP30PTGER4 | |
| SCHEMBL4055519 | 0.79 | CNR1 (0.79) | CNR1CNR2HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |