SCHEMBL30446074

SCHEMBL30446074

CCCCn1nc(C(=O)N[C@@H](Cc2ccccc2)C(N)=O)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 13/20 1.00
▸ CNR2 P34972 9/20 1.00
▸ HTR3A P46098 1/20 0.45
▸ MEN1 O00255 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ CA12 O43570 1/20 0.44
▸ CA1 P00915 1/20 0.44
▸ CA9 Q16790 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ CAPN1 P07384 1/20 0.43
▸ CTSB P07858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4053457 0.88 CNR1 (0.79) CNR1CNR2HTR3ACAPN1CTSB
SCHEMBL4051770 0.87 CNR1 (0.77) CNR1CNR2HTR3AMEN1KMT2A
SCHEMBL21178272 0.85 CNR1 (0.74) CNR1CNR2HTR3AKDM4E
SCHEMBL21178271 0.85 CNR1 (0.74) CNR1CNR2HTR3AKDM4E
SCHEMBL25368841 0.84 CNR1 (0.74) CNR1CNR2HTR3AKDM4E
SCHEMBL25368839 0.84 CNR1 (0.74) CNR1CNR2HTR3AKDM4E
SCHEMBL29275142 0.81 CNR1 (1.00) CNR1CNR2HTR3AKDM4E
SCHEMBL30609587 0.81 CNR1 (1.00) CNR1CNR2HTR3AKDM4E
SCHEMBL12884556 0.81 CNR1 (0.71) CNR1CNR2MEN1KMT2A
SCHEMBL25369148 0.81 CNR1 (0.71) CNR1CNR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646477-A2 METHODS AND COMPOSITIONS FOR DISPLAYING PEPTIDE LIBRARIES Board of Regents, The University of Texas System (US) 2025-11-12 — — EP disclosed
US-20250027072-A1 METHODS AND COMPOSITIONS RELATED TO ENGINEERED CANNABINOID RECEPTORS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2025-01-23 — — US disclosed
EP-4441203-A1 METHODS AND COMPOSITIONS RELATED TO ENGINEERED CANNABINOID RECEPTORS Board of Regents, The University of Texas System (US) 2024-10-09 — — EP disclosed
WO-2024148130-A2 METHODS AND COMPOSITIONS FOR DISPLAYING PEPTIDE LIBRARIES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-07-11 — — WO disclosed
WO-2023102541-A1 METHODS AND COMPOSITIONS RELATED TO ENGINEERED CANNABINOID RECEPTORS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-06-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250027072-A1 METHODS AND COMPOSITIONS RELATED TO ENGINEERED CANNABINOID RECEPTORS CNR1, CNR2, GPR3 CNR1 1/4885CNR2 2/4885HTR3A 284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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