SCHEMBL40518

SCHEMBL40518

Nc1ncc(Br)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrogen SCHEMBL28139007 0.94 HTT (0.44)
SCHEMBL29278000 0.81 HTT (0.35)
SCHEMBL1198596 0.73 NPC1 (0.55)
SCHEMBL4859450 0.72 MAP4K4 (0.56)
SCHEMBL2495212 0.72
SCHEMBL198651 0.72
SCHEMBL29549225 0.67
SCHEMBL2110297 0.67
SCHEMBL1163318 0.67
SCHEMBL105422 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1689 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119613346-A Method for preparing 5-bromopyrimidine 上海沃缨生物科技有限公司 2025-03-14 CN claimed
CN-119281138-A Core-shell structure porous polymer-carbon nano tube filter membrane and preparation method thereof 国能神东煤炭集团有限责任公司 2025-01-10 CN claimed
CN-118812574-A Refining process of intermediate of anticancer drug Apitolisib 山东省科学院菏泽分院 2024-10-22 CN claimed
US-20230295144-A1 2-polysubstituted aromatic ring-pyrimidine derivatives, preparation and medical application thereof UNIV ZHEJIANG (CN) 2023-09-21 US claimed
CN-113683571-B Preparation method of 2-methyl-5-bromopyrimidine 上海日异生物科技有限公司 2023-02-28 CN claimed
CN-111018858-B Heterocyclic derivative and preparation method and application thereof 复旦大学 2022-11-18 CN claimed
CN-113549254-B Method for preparing modified vulcanized rubber and modified vulcanized rubber 中国科学技术大学 2022-10-28 CN claimed
CN-106632443-B Synthesis method of 2-aminopyrimidine-5-boric acid pinacol borate 山东友帮生化科技有限公司 2022-06-17 CN claimed
EP-3530656-B1 2-SUBSTITUTED AROMATIC RING-PYRIMIDINE DERIVATIVE, AND PREPARATION AND APPLICATION THEREOF UNIV ZHEJIANG (CN) 2022-01-05 EP claimed
CN-113683571-A Preparation method of 2-methyl-5-bromopyrimidine 上海日异生物科技有限公司 2021-11-23 CN claimed
US-20040202825-A1 RECORDING SHEETS CONTAINING PURINE, PYRIMIDINE, BENZIMIDAZOLE, IMIDAZOLIDINE, URAZOLE, PYRAZOLE, TRIAZOLE, BENZOTRIAZOLE, TETRAZOLE, AND PYRAZINE COMPOUNDS XEROX CORPORATION 2004-10-14 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0673783-B1 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORP (US) 2000-07-05 EP claimed
US-5659348-A APPLYING TO A SUBSTRATE XEROX CORPORATION (US) 1997-08-19 US claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed