Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | DRD2 | P14416 | 6/20 | 0.44 |
| ▸ | DRD3 | P35462 | 6/20 | 0.44 |
| ▸ | GRM5 | P41594 | 8/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28474185 | 0.85 | MAPK1 (0.68) | MAPK1DRD2DRD3GRM5NPC1 | |
| SCHEMBL30513269 | 0.81 | MAPK1 (0.63) | MAPK1DRD2DRD3GRM5NPC1 | |
| SCHEMBL24576867 | 0.77 | DRD2 (0.51) | MAPK1DRD2DRD3GRM5 | |
| SCHEMBL30916184 | 0.77 | MAPK1 (0.58) | MAPK1GRM5 | |
| SCHEMBL741598 | 0.77 | MAPK1 (0.58) | MAPK1GRM5 | |
| SCHEMBL13413141 | 0.75 | MAPK1 (0.59) | MAPK1DRD2DRD3GRM5NPC1 | |
| SCHEMBL30513280 | 0.75 | MAPK1 (0.55) | MAPK1DRD2DRD3GRM5 | |
| SCHEMBL17613234 | 0.74 | DRD2 (0.50) | MAPK1DRD2DRD3GRM5FGFR1 | |
| SCHEMBL30861099 | 0.72 | MAPK1 (0.52) | MAPK1DRD2DRD3GRM5NPC1 | |
| SCHEMBL16765902 | 0.72 | MEN1 (0.53) | MAPK1DRD2DRD3GRM5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049548-A1 | FUSED OXAZOLES & THIAZOLES AS HISTAMINE H3- RECEPTOR LIGANDS | UCB Pharma, S.A. (BE) | 2009-04-22 | — | — | EP | claimed |
| WO-2008012010-A1 | FUSED OXAZOLES & THIAZOLES AS HISTAMINE H3- RECEPTOR LIGANDS | UCB PHARMA, S.A. (BE) | 2008-01-31 | — | — | WO | claimed |
| CN-118019735-A | Arylsulfonyl compounds as CCR6 inhibitors | 坎莫森特里克斯公司 | 2024-05-10 | — | — | CN | disclosed |