Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.82 |
| ▸ | RAF1 | P04049 | 1/20 | 0.55 |
| ▸ | BRAF | P15056 | 1/20 | 0.55 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | ABL2 | P42684 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2082534 | 0.91 | MAPK14 (0.86) | MAPK14RAF1BRAFEPHB2ABL1 | |
| SCHEMBL2082516 | 0.91 | MAPK14 (1.00) | MAPK14RAF1BRAFEPHB2ABL1 | |
| SCHEMBL2081099 | 0.89 | MAPK14 (0.78) | MAPK14RAF1BRAFEPHB2ABL1 | |
| SCHEMBL2080330 | 0.88 | MAPK14 (0.77) | MAPK14RAF1BRAFEPHB2ABL1 | |
| SCHEMBL4302272 | 0.88 | MAPK14 (0.74) | MAPK14RAF1BRAFEPHB2ABL1 | |
| SCHEMBL2082797 | 0.86 | MAPK14 (0.74) | MAPK14RAF1BRAFEPHB2ABL1 | |
| SCHEMBL4049433 | 0.85 | MAPK14 (0.81) | MAPK14RAF1BRAFEPHB2ABL1 | |
| SCHEMBL2080624 | 0.85 | MAPK14 (0.73) | MAPK14RAF1BRAFEPHB2ABL1 | |
| SCHEMBL2084044 | 0.84 | MAPK14 (0.86) | MAPK14RAF1BRAFEPHB2ABL1 | |
| SCHEMBL2079794 | 0.83 | MAPK14 (0.59) | MAPK14RAF1BRAFEPHB2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836173-A4 | ANTI-INFLAMMATORY MEDICAMENTS | DECIPHERA PHARMACEUTICALS LLC (US) | 2009-07-08 | — | — | EP | claimed |
| EP-1836173-A2 | ANTI-INFLAMMATORY MEDICAMENTS | Deciphera Pharmaceuticals, LLC (US) | 2007-09-26 | — | — | EP | claimed |
| WO-2006081034-A2 | ANTI-INFLAMMATORY MEDICAMENTS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2006-08-03 | — | — | WO | claimed |
| US-20090312349-A1 | ANTI-INFLAMMATORY MEDICAMENTS | DECIPHERA PHARMACEUTICALS, LLC | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312349-A1 | ANTI-INFLAMMATORY MEDICAMENTS | ABL2, ABL1, PTK2 | MAPK14 80/4885RAF1 189/4885BRAF 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.