SCHEMBL4049433

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2082042	0.91	MAPK14 (0.86)	MAPK14RAF1BRAFEPHB2GRM5
	SCHEMBL2081541	0.90	MAPK14 (1.00)	MAPK14RAF1BRAFEPHB2GRM5
	SCHEMBL2082364	0.88	MAPK14 (0.77)	MAPK14RAF1BRAFEPHB2GRM5
	SCHEMBL2081766	0.87	MAPK14 (0.82)	MAPK14RAF1BRAFEPHB2ABL1
	SCHEMBL4052308	0.85	MAPK14 (0.82)	MAPK14RAF1BRAFEPHB2ABL1
	SCHEMBL2080577	0.85	MAPK14 (0.73)	MAPK14RAF1BRAFEPHB2GRM5
	SCHEMBL13576980	0.85	MAPK14 (0.72)	MAPK14GRM5PTPN1ABL1ABL2
	SCHEMBL2082683	0.84	MAPK14 (0.75)	MAPK14RAF1BRAFEPHB2GRM5
	SCHEMBL2081435	0.84	MAPK14 (0.74)	MAPK14RAF1BRAFEPHB2GRM5
	SCHEMBL4298803	0.83	PTPN1 (0.64)	MAPK14GRM5PTPN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.