Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 16/20 | 0.59 |
| ▸ | CNR2 | P34972 | 13/20 | 0.57 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690944 | 0.94 | CNR1 (0.51) | CNR1CNR2HTR3A | |
| SCHEMBL13690899 | 0.89 | CNR1 (0.62) | CNR1CNR2HTR3A | |
| SCHEMBL4047757 | 0.87 | CNR1 (0.45) | CNR1CNR2HTR3A | |
| SCHEMBL4049649 | 0.85 | CNR1 (0.80) | CNR1CNR2HTR3A | |
| SCHEMBL13690903 | 0.83 | CNR2 (0.47) | CNR1CNR2HTR3A | |
| SCHEMBL4055098 | 0.83 | CNR2 (0.47) | CNR1CNR2HTR3A | |
| SCHEMBL4055519 | 0.82 | CNR1 (0.79) | CNR1CNR2HTR3A | |
| SCHEMBL1218262 | 0.81 | CNR1 (0.63) | CNR1CNR2 | |
| SCHEMBL1217864 | 0.80 | CNR1 (0.55) | CNR1CNR2HTR3A | |
| SCHEMBL4057194 | 0.79 | CNR1 (0.60) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |