Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 13/20 | 0.45 |
| ▸ | CNR2 | P34972 | 13/20 | 0.45 |
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690890 | 0.90 | CNR1 (0.47) | CNR1CNR2CFDHTR3A | |
| SCHEMBL4052367 | 0.87 | CNR1 (0.59) | CNR1CNR2HTR3A | |
| SCHEMBL13690944 | 0.86 | CNR1 (0.51) | CNR1CNR2HTR3A | |
| SCHEMBL1218497 | 0.81 | MEN1 (0.50) | CNR1CNR2CFDCTSD | |
| SCHEMBL1218526 | 0.80 | CNR2 (0.46) | CNR1CNR2CFD | |
| SCHEMBL13690527 | 0.80 | CNR1 (0.47) | CNR1CNR2 | |
| SCHEMBL13690903 | 0.80 | CNR2 (0.47) | CNR1CNR2HTR3A | |
| SCHEMBL4055098 | 0.80 | CNR2 (0.47) | CNR1CNR2HTR3A | |
| SCHEMBL4050221 | 0.79 | CNR1 (0.46) | CNR1CNR2 | |
| SCHEMBL13691225 | 0.79 | CNR1 (0.46) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |