Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 2/20 | 0.41 |
| ▸ | FNTB | P49356 | 2/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.41 |
| ▸ | OTC | P00480 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 3/20 | 0.40 |
| ▸ | NOS1 | P29475 | 3/20 | 0.40 |
| ▸ | NOS2 | P35228 | 3/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | BHMT | Q93088 | 3/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL18660568 | 1.00 | ALOX15 (0.49) | ALOX15BLMPMP22KMT2AFNTA | |
| Arginine SCHEMBL6517506 | 1.00 | ALOX15 (0.49) | ALOX15BLMPMP22KMT2AFNTA | |
| Arginine SCHEMBL4059260 | 0.96 | ALOX15 (0.45) | ALOX15BLMPMP22KMT2AFNTA | |
| Arginine SCHEMBL458502 | 0.96 | ALOX15 (0.45) | ALOX15BLMPMP22KMT2AFNTA | |
| Arginine SCHEMBL13684847 | 0.93 | OTC (0.46) | KMT2AFNTAFNTBPGGT1BOTC | |
| Arginine SCHEMBL15194117 | 0.93 | OTC (0.46) | KMT2AFNTAFNTBPGGT1BOTC | |
| Arginine SCHEMBL9234547 | 0.93 | OTC (0.46) | KMT2AFNTAFNTBPGGT1BOTC | |
| Arginine SCHEMBL1766048 | 0.93 | OTC (0.46) | KMT2AFNTAFNTBPGGT1BOTC | |
| Arginine SCHEMBL1766047 | 0.93 | OTC (0.46) | KMT2AFNTAFNTBPGGT1BOTC | |
| Arginine SCHEMBL20138208 | 0.92 | ALOX15 (0.41) | ALOX15BLMPMP22KMT2AFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3271012-A1 | METHODS OF PROVIDING SKIN CARE USING PHOTOTHERAPY | Inderm (FR) | 2018-01-24 | — | — | EP | disclosed |
| WO-2016146778-A1 | METHODS OF PROVIDING SKIN CARE USING PHOTOTHERAPY | INDERM (FR) | 2016-09-22 | — | — | WO | disclosed |
| EP-2035443-A1 | STABILIZED VITAMIN C DERIVATIVES HAVING A PEPTIDE MOLECULE, PREPARATION METHOD THEREOF, AND COMPOSITION CONTAINING THE SAME | Peptron Co., Ltd. (KR) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007148847-A1 | STABILIZED VITAMIN C DERIVATIVES HAVING A PEPTIDE MOLECULE, PREPARATION METHOD THEREOF, AND COMPOSITION CONTAINING THE SAME | PEPTRON CO., LTD. (KR) | 2007-12-27 | — | — | WO | disclosed |