SCHEMBL4052780

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4302770	0.89	NTRK1 (0.73)	NTRK1MAPK14MAPK13MAPK12MAPK11
	SCHEMBL4295121	0.87	NTRK1 (0.58)	NTRK1MAPK14MAPK13MAPK12MAPK11
	SCHEMBL4223376	0.86	MAPK14 (0.73)	NTRK1MAPK14MAPK13MAPK12MAPK11
	SCHEMBL13576982	0.85	MAPK14 (0.61)	NTRK1MAPK14MAPK13MAPK12MAPK11
	SCHEMBL16317154	0.84	MAPK14 (0.56)	NTRK1MAPK14MAPK13MAPK12MAPK11
	SCHEMBL4307722	0.80	MAPK14 (0.63)	NTRK1MAPK14MAPK13MAPK12MAPK11
	SCHEMBL3296515	0.78	MAPK14 (0.78)	NTRK1MAPK14MAPK13MAPK12MAPK11
	SCHEMBL2085677	0.76	RAB9A (0.56)	—
	SCHEMBL16585636	0.76	NTRK1 (1.00)	NTRK1MAPK14MAPK13MAPK12MAPK11
	SCHEMBL3190594	0.75	MAPK14 (0.57)	NTRK1MAPK14MAPK13MAPK12MAPK11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.