Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.59 |
| ▸ | CNR2 | P34972 | 6/20 | 0.59 |
| ▸ | HTR3A | P46098 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048639 | 0.97 | CNR1 (0.58) | CNR1CNR2HTR3AKDM4ESCN9A | |
| SCHEMBL4050521 | 0.95 | CNR1 (0.58) | CNR1CNR2HTR3AKDM4EROCK1 | |
| SCHEMBL4051603 | 0.93 | CNR1 (0.58) | CNR1CNR2HTR3AKDM4EROCK1 | |
| SCHEMBL13690974 | 0.93 | CNR1 (0.58) | CNR1CNR2HTR3AKDM4EROCK1 | |
| SCHEMBL4052970 | 0.91 | CNR1 (0.58) | CNR1CNR2HTR3AKDM4EROCK1 | |
| SCHEMBL4058950 | 0.89 | CNR1 (0.59) | CNR1CNR2HTR3AKDM4EROCK1 | |
| SCHEMBL13690943 | 0.89 | CNR1 (0.64) | CNR1CNR2HTR3AKDM4ESCN9A | |
| SCHEMBL4057476 | 0.89 | CNR1 (0.61) | CNR1CNR2HTR3AKDM4E | |
| SCHEMBL4050074 | 0.89 | CNR1 (0.57) | CNR1CNR2HTR3AKDM4EROCK1 | |
| SCHEMBL4050224 | 0.88 | CNR1 (0.64) | CNR1CNR2HTR3AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |