Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.59 |
| ▸ | CNR2 | P34972 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050950 | 0.97 | CNR1 (0.58) | CNR1CNR2KDM4EHTR3AROCK1 | |
| SCHEMBL13690913 | 0.97 | CNR1 (0.58) | CNR1CNR2KDM4EHTR3AROCK1 | |
| SCHEMBL4050224 | 0.92 | CNR1 (0.64) | CNR1CNR2KDM4EHTR3A | |
| SCHEMBL4052970 | 0.91 | CNR1 (0.58) | CNR1CNR2KDM4EHTR3AROCK1 | |
| SCHEMBL4059339 | 0.89 | CNR1 (0.62) | CNR1CNR2KDM4EHTR3A | |
| SCHEMBL4053834 | 0.89 | CNR1 (0.62) | CNR1CNR2KDM4EHTR3A | |
| SCHEMBL4053153 | 0.89 | CNR1 (0.59) | CNR1CNR2KDM4EHTR3AROCK1 | |
| SCHEMBL4050074 | 0.89 | CNR1 (0.57) | CNR1CNR2KDM4EHTR3AROCK1 | |
| SCHEMBL4050521 | 0.88 | CNR1 (0.58) | CNR1CNR2KDM4EHTR3AROCK1 | |
| SCHEMBL4048639 | 0.86 | CNR1 (0.58) | CNR1CNR2KDM4EHTR3AROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |