Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.59 |
| ▸ | CCR1 | P32246 | 5/20 | 0.45 |
| ▸ | CTSS | P25774 | 7/20 | 0.43 |
| ▸ | CTSL | P07711 | 5/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.42 |
| ▸ | FAP | Q12884 | 2/20 | 0.42 |
| ▸ | CTSV | O60911 | 3/20 | 0.42 |
| ▸ | LONP1 | P36776 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4037909 | 0.94 | CTSK (0.55) | CTSKCCR1CTSSCTSLPREP | |
| SCHEMBL4040279 | 0.93 | CTSK (0.54) | CTSKCCR1CTSSCTSLPREP | |
| SCHEMBL4041248 | 0.93 | CTSK (0.55) | CTSKCCR1CTSSCTSLPREP | |
| SCHEMBL4044295 | 0.93 | CTSK (0.66) | CTSKCCR1CTSSCTSLPREP | |
| SCHEMBL4040591 | 0.92 | CTSK (0.53) | CTSKCCR1CTSSCTSLPREP | |
| SCHEMBL4041590 | 0.92 | CTSK (0.66) | CTSKCCR1CTSSCTSLPREP | |
| SCHEMBL4045453 | 0.92 | CTSK (0.56) | CTSKCCR1CTSSCTSLPREP | |
| SCHEMBL4044657 | 0.91 | CTSK (0.52) | CTSKCCR1CTSSCTSLPREP | |
| SCHEMBL4046526 | 0.91 | CTSK (0.72) | CTSKCCR1CTSSCTSLCTSV | |
| SCHEMBL4037045 | 0.91 | CTSK (0.72) | CTSKCCR1CTSSCTSLCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |