SCHEMBL4053759

SCHEMBL4053759

O=C(O)[C@H]1C[C@@H]2CCCN2C1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.49
GAA P10253 2/20 0.41
POLB P06746 1/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
KDM2B Q8NHM5 5/20 0.38
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
HRH1 P35367 1/20 0.37
HTR2B P41595 1/20 0.37
AGTR2 P50052 4/20 0.36
MC4R P32245 2/20 0.36
MC3R P41968 2/20 0.36
MC1R Q01726 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3731529 1.00 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2GAAPOLBMEN1
SCHEMBL10804427 1.00 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2GAAPOLBMEN1
SCHEMBL10804405 1.00 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2GAAPOLBMEN1
Hydrochloric Acid SCHEMBL9864402 0.98 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2GAAPOLBMEN1
Hydrochloric Acid SCHEMBL9864395 0.98 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2GAAPOLBMEN1
Hydrochloric Acid SCHEMBL9864264 0.98 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2GAAPOLBMEN1
Hydrochloric Acid SCHEMBL9864399 0.98 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2GAAPOLBMEN1
SCHEMBL29556804 0.87 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2GAAPOLBMEN1
SCHEMBL10859973 0.83 ALDH1A1 (0.71) ALDH1A1SMN1; SMN2GAAMEN1KMT2A
SCHEMBL29588116 0.80 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2GAAPOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009122433-A3 A PROCESS FOR PREPARATION OF RAMIPRIL IPCA LABORATORIES LIMITED (IN) 2014-09-04 WO disclosed
WO-2009122433-A2 A PROCESS FOR PREPARATION OF RAMIPRIL IPCA LABORATORIES LIMITED (IN) 2009-10-08 WO disclosed