Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11842785 | 0.95 | MAPT (0.52) | MAPTKMT2AMEN1KDM4ELMNA | |
| SCHEMBL4059775 | 0.89 | MAPT (0.47) | MAPTKMT2AMEN1KDM4ELMNA | |
| SCHEMBL4279296 | 0.85 | MAPT (0.57) | MAPTKMT2AMEN1KDM4ELMNA | |
| SCHEMBL10771702 | 0.85 | MAPT (0.57) | MAPTKMT2AMEN1KDM4ELMNA | |
| SCHEMBL4136472 | 0.84 | ALDH1A1 (0.58) | MAPTKMT2AKDM4ELMNACRHBP | |
| SCHEMBL14861589 | 0.84 | MAPT (0.65) | MAPTKMT2AMEN1KDM4ELMNA | |
| SCHEMBL2614715 | 0.83 | MEN1 (0.59) | MAPTKMT2AMEN1KDM4ELMNA | |
| SCHEMBL8593569 | 0.83 | MEN1 (0.59) | MAPTKMT2AMEN1KDM4ELMNA | |
| SCHEMBL20448296 | 0.83 | MAPT (0.56) | MAPTKMT2AMEN1KDM4ELMNA | |
| SCHEMBL5611041 | 0.83 | MAPT (0.54) | MAPTKMT2AMEN1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |