SCHEMBL4053863

SCHEMBL4053863

COC(CCC(C)=O)CC(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
TDP1 Q9NUW8 1/20 0.36
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
CA1 P00915 2/20 0.32
CTSK P43235 1/20 0.32
KISS1R Q969F8 1/20 0.32
CACNA2D1 P54289 2/20 0.31
CACNB3 P54284 1/20 0.31
CACNA1C Q13936 1/20 0.31
PGR P06401 1/20 0.31
ADRA1A P35348 1/20 0.31
HTR2B P41595 1/20 0.31
CACNA2D2 Q9NY47 1/20 0.31
RNPEP Q9H4A4 1/20 0.31
SLC7A5 Q01650 1/20 0.31
LMNA P02545 1/20 0.31
SLC15A2 Q16348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4054598 0.88 KDM1A (0.37) ALDH1A1TDP1MGAMGAASI
SCHEMBL16171990 0.82 CA1 (0.31) CA1CTSKCACNA2D1CACNB3CACNA1C
SCHEMBL4059679 0.80 TDP1 (0.33) TDP1CA1CTSK
SCHEMBL4059136 0.78 ALDH1A1 (0.50) ALDH1A1TDP1MGAMGAASI
SCHEMBL13174025 0.77 ALDH1A1 (0.38) ALDH1A1MGAMGAASIMGAM2
SCHEMBL19546336 0.75 ALDH1A1 (0.36) ALDH1A1MGAMGAASIMGAM2
SCHEMBL1658171 0.73 ALDH1A1 (0.33) ALDH1A1
SCHEMBL1783436 0.73 ALDH1A1 (0.43) ALDH1A1TDP1CA1KISS1RCACNA2D1
SCHEMBL10439675 0.73
SCHEMBL12039727 0.72 ALDH1A1 (0.30) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed