Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 20/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054033 | 0.87 | SLC6A2 (0.68) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL4053887 | 0.85 | SLC6A2 (0.46) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL4059296 | 0.84 | SLC6A2 (0.71) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL4053618 | 0.81 | SLC6A2 (0.74) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL4053530 | 0.81 | SLC6A2 (0.72) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL4947356 | 0.80 | SLC6A2 (0.70) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL4055131 | 0.80 | SLC6A2 (0.65) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL4059516 | 0.79 | SLC6A2 (0.67) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL4052758 | 0.78 | SLC6A2 (0.56) | SLC6A2SLC6A3SLC6A4KCNH2 | |
| SCHEMBL4064534 | 0.78 | SLC6A2 (0.69) | SLC6A2SLC6A3SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061776-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | Wyeth a Corporation of the State of Delaware (US) | 2009-05-27 | — | — | EP | claimed |
| WO-2008073459-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-06-19 | — | — | WO | claimed |
| EP-2061776-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | Wyeth a Corporation of the State of Delaware (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008073459-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |